• Daisy@feiyuebio.com

[email protected]

Date : March 30, 2022
Products & Services : Lifes cience research test Kits: Antibodies - ELISA - Protein
Supply Chain : Manufacturer, Producer

Description

Mouse IL-1α(Interleukin 1 Alpha) ELISA Kit

Basic information

Interleukin 1 alpha (IL-1α) also known as hematopoietin 1 is a cytokine of the interleukin 1 family that in humans is encoded by the IL1A gene.[5][6] In general, Interleukin 1 is responsible for the production of inflammation, as well as the promotion of fever and sepsis. IL-1α inhibitors are being developed to interrupt those processes and treat diseases.IL-1α is produced mainly by activated macrophages, as well as neutrophils, epithelial cells, and endothelial cells. It possesses metabolic, physiological, haematopoietic activities, and plays one of the central roles in the regulation of the immune responses. It binds to the interleukin-1 receptor. It is on the pathway that activates tumor necrosis factor-alpha.IL-1α is also known as fibroblast-activating factor (FAF), lymphocyte-activating factor (LAF), B-cell-activating factor (BAF), leukocyte endogenous mediator (LEM), epidermal cell-derived thymocyte-activating factor (ETAF), serum amyloid A inducer or hepatocyte-stimulating factor (HSP), catabolin, hemopoetin-1 (H-1), endogenous pyrogen (EP), and proteolysis-inducing factor (PIF).

Feiyue’s Mouse IL-19(Interleukin 19) is an ELISA reagent for detection of IL-19(Interleukin 19) in serum, plasma, tissue homogenates, cell lysates, cell culture supernates and other biological fluids.

Mouse IL-19(Interleukin 19)-specific monoclonal antibody has been pre-coated in the wells of the supplied microplate. Standards samples and controls are added to interact with the immobilized antibody. A sandwich complex is formed by additional anti-Mouse IL-19(Interleukin 19) antibody with HRP-Streptavidin. TMB solution is added to react with the sandwich for ming optical signal measured by microplate reader. The concentMouseion of Mouse IL-19(Interleukin 19) in the sample can be calculated by comparing the absorbance of the sample with the standard curve.

 

Reference:

1. “Human PubMed Reference:”. National Center for Biotechnology Information, U.S. National Library of Medicine.

2, “Mouse PubMed Reference:”. National Center for Biotechnology Information, U.S. National Library of Medicine.

3, Nicklin MJ, Weith A, Duff GW (Jan 1994). “A physical map of the region encompassing the human interleukin-1 alpha, interleukin-1 beta, and interleukin-1 receptor antagonist genes”. Genomics. 19 (2): 382–4. doi:10.1006/geno.1994.1076. PMID 8188271.


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